Noninvasive hemodynamic insight for heart failure care
Coredio estimates catheter-grade intracardiac hemodynamics from wearables, using AI and physics-based digital twins.

What Coredio is
Coredio CPSE, the Cardiac Performance Simulation Engine, builds a personalized digital twin of each patient’s cardiovascular system,
turning everyday wearable data into the intracardiac measures clinicians rely on for guideline-directed medical therapy. No implant. No procedure.
The challenge
Cardiac monitoring today is fragmented, costly, and invasive

Insufficient monitoring

Limited access between visits


Invasive and costly
The platform solution
Noninvasive, personalized heart monitoring through AI, digital twins, and everyday wearables.
Learn more
Patient eligibility
The solution
Catheter-grade hemodynamics, anywhere the patient is
Left Ventricular End-Diastolic Pressure (LVEDP) rises before symptoms appear, flagging worsening heart failure early.

Cardiac Index (CI) scales cardiac output to body size, showing whether blood flow is meeting metabolic demand.

Central Venous Pressure (CVP) signals volume overload or right heart strain, an early indicator of decompensation.

Elevated Systemic Vascular Resistance (SVR) increases cardiac workload and reduces output, a marker of worsening heart failure.





Monitoring workflow
A simple workflow that fits existing care, without added complexity



Patient personalization
During routine initial checkups, Coredio automatically builds a personalized patient model in the background.
Home setup
Patients are set up with a smartwatch and BP cuff for home use. Coredio provides a watch if they don't have one.
Remote monitoring
Coredio estimates hemodynamic status from daily smartwatch and blood pressure readings.
Clinical review & reporting
Care teams review patient-specific alerts and intervene early.
Precision
Coredio’s technology features
Validated Against Catheterization
Spot-Check Hemodynamic Status
Catheter-Grade Estimates
Testimonial
Built for the entire care continuum

“Coredio’s wearable-derived signals and physics-informed AI could help close the gap between hospital-based measurements and at-home heart failure monitoring, giving clinicians earlier visibility into patient physiology. FDA Breakthrough Device Designation reflects the clinical need this technology addresses.”
Dr. Jagmeet P. Singh, MGH
Mass General Brigham
Frequently asked questions
No. Coredio is entirely noninvasive. It relies on wearable sensors such as a smartwatch and a blood pressure cuff. There are no implants, catheters, or surgical procedures involved.
Every heart is different. Coredio builds a model from your own baseline measurements, then tracks your individual cardiovascular trends over time and shares them with your clinician. The aim is earlier, smarter intervention before a small change becomes a serious one.
A compatible smartwatch and a blood pressure cuff. If you don't already have a watch, we'll provide one as part of your home setup.
Coredio is designed for clinicians managing heart failure patients and for the patients themselves who benefit from at-home hemodynamic monitoring.
Connect
with the Coredio team
Join the clinicians who are exploring the future of cardiovascular monitoring










