Coredio estimates the pressures and blood flow inside the heart from wearables, using AI and a digital twin of each patient.
Breakthrough Device Designation
Granted
March
2026
What Coredio is
Coredio CPSE, the Cardiac Performance Simulation Engine, builds a digital twin of each patient’s heart and circulation,
turning everyday wearable data into the heart measurements clinicians use to guide treatment. No implant. No procedure..
- Physics-based digital twin
- Trained on clinical data
- Watch and cuff inputs
- LVEDP, CVP, CI, SVR
The challenge with the current standard of care
Heart monitoring today is fragmented, costly, and invasive
Too little monitoring
Heart failure care still has no good standard for day-to-day monitoring.
Limited access between visits
Without an echo or cath, care teams can't see how the heart is really doing.
Invasive and costly
Getting accurate data at home today means an expensive implant.
Our platform
Personalized heart monitoring with no implant, built on AI, digital twins, and everyday wearables.
Patient eligibility
Quick personalization
At-home checks
Data collection
Live heart data from a watch and cuff.
Clear insight
Clear analysis that helps care teams decide what to do next.
CPSE Algorithm
Turns heart data into numbers clinicians can use.
Hemodynamic status
Real-time blood flow & vitals.
Data collection
Live heart data from a watch and cuff.
Clear insight
Clear analysis that helps care teams decide what to do next.
CPSE Algorithm
Turns heart data into numbers clinicians can use.
Hemodynamic status
Real-time blood flow & vitals.
Our solution
Catheter-grade heart data, anywhere the patient is.
CVP
Central Venous Pressure (CVP) shows fluid overload or right heart strain, an early sign a patient is getting worse.
SVR
High Systemic Vascular Resistance (SVR) makes the heart work harder and pump less, a sign heart failure is getting worse.
LVEDP
Left Ventricular End-Diastolic Pressure (LVEDP) predicts worsening heart failure before symptoms start.
CI
Cardiac Index (CI) is blood flow adjusted for body size. It shows whether the body is getting the blood it needs.
How monitoring works
A simple workflow that fits into the care teams already provide
Personal setup
Before discharge, Coredio builds a personal model of the patient's heart in a few minutes.
Our ecosystem
A connected ecosystem that is rigorous for clinicians and simple for patients.
What clinicians say
Built for every step of heart failure care
“Coredio’s wearable-derived signals and physics-informed AI could help close the gap between hospital-based measurements and at-home heart failure monitoring, giving clinicians earlier visibility into patient physiology. FDA Breakthrough Device Designation reflects the clinical need this technology addresses.”
Dr. Jagmeet P. Singh, MGH
Mass General Brigham
Frequently asked questions
A compatible smartwatch and a blood pressure cuff. If you do not already have a watch, we provide one as part of the home setup.
Connect with the Coredio team
Join the clinicians exploring a better way to monitor heart failure
FDA | Disclaimer:
Coredio CPSE™ has received FDA Breakthrough Device Designation. The device is not yet cleared by the FDA for commercial use. Indications for Use are subject to FDA review under the 510(k) process.